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Nothing can protect portable drives better than this software.
As far as I have researched and used different software to secure portable drives, USB Secure is probably the best one available on the market at the moment. It does not only provides protection to USB drives, but, all the portable drives that are being used around the globe. It is extremely easy to use and extremely difficult to hack. I will highly recommend it to all those, who want to secure their portable drives.
Pros: 1. It is PC independent and is a plug and play program
2. Allows me to open fine in just read only format
3. Free of complexities
Cons: It is hard to say if there are any cons because I have not experienced any yet.